Flublok Premium Influenza vaccine receives FDA approval for an expanded age indication

April 8, 2025
Leslie Parrish Fuchs

A New FDA Approval for Flublok Influenza Vaccine!

The wholly unique premium flu vaccine Flublok (RIV3) has received an expanded age indication to include patients all the way down to 9 years of age! Updated Flublok Prescribing Information

Although there are other premium flu vaccines available in the United States, sometimes referred to as “Senior Flu Vaccines”,  Sanofi’s Fluzone High-Dose and CSL Seqirus’s FLUAD, they currently are only indicated for patients 65 years and older. 

Having a flu vaccine available in this category of influenza vaccines for the younger patients is refreshing, particularly due to the irascible nature of the influenza virus. 

Flublok is not made with eggs, therefore it’s an option to consider for those with severe egg allergies.  Additionally, the recombinant DNA technology may have the theoretical advantage of reducing the likelihood of antigenic drift or antigenic shift during the manufacturing process that some mention could be an issue with flu vaccines made with eggs. Lastly, each dose of Flublok packs an impressive punch of 45 mcgs of antigen per strain.  For comparison, Sanofi’s Fluzone High-Dose has 60 mcgs/strain and standard flu vaccines have 15 mcgs/strain.

Fortunately, we have flu vaccines and a nice variety of influenza vaccines to choose from. All flu vaccines have something to offer and fortunately they all deliver a reduced risk of adverse outcomes that can come with an influenza infection.  Please review the prescribing information as well as the ACIP recommendations on the use of influenza vaccines and those specific vaccines under consideration. Influenza vaccines are seasonal so make sure to examine the 2025-2026 aforementioned information when available.

Flublok discounts, as well as other flu vaccine discounts, can be accessed without fees through a Physicians’ Buying Group/PracticeWell program.  Join PracticeWell today!